abstract：:The PREDIMED (PREvención con DIeta MEDiterránea) multicenter, randomized, primary prevention trial assessed the long-term effects of the Mediterranean diet (MeDiet) on clinical events of cardiovascular disease (CVD). We randomized 7447 men and women at high CVD risk into three diets: MeDiet supplemented with extra-vir...

journal_title：Progress in cardiovascular diseases

authors： Martínez-González MA,Salas-Salvadó J,Estruch R,Corella D,Fitó M,Ros E,PREDIMED INVESTIGATORS.

更新日期：2015-07-01 00:00:00

abstract：:Positron-emitting myocardial flow radiotracers such as (15)O-water, (13)N-ammonia and (82)Rubidium in conjunction with positron-emission-tomography (PET) are increasingly applied in clinical routine for coronary artery disease (CAD) detection, yielding high diagnostic accuracy, while providing valuable information on ...

journal_title：Progress in cardiovascular diseases

authors： Schindler TH

更新日期：2015-05-01 00:00:00

abstract：:Coronary computed tomography angiography (CTA) offers a non-invasive method to detect coronary plaque and stenosis. However, to date, CTA has been most useful as a method of ruling out coronary artery disease (CAD) among patients with low to intermediate pretest probability of significant CAD. The reduced specificity ...

journal_title：Progress in cardiovascular diseases

authors： Hulten E,Ahmadi A,Blankstein R

更新日期：2015-05-01 00:00:00

abstract：:Microbubbles are an excellent intravascular tracer, and both the rate of myocardial opacification (analogous to coronary microvascular perfusion) and contrast intensity (analogous to myocardial blood volume) provide unique insights into myocardial perfusion. A strong evidence base has been accumulated to show comparab...

journal_title：Progress in cardiovascular diseases

authors： Pathan F,Marwick TH

更新日期：2015-05-01 00:00:00

abstract：:There has been a lot of progress in measurement techniques of the pulmonary circulation in recent years, and this has required updating of basic physiological knowledge. Pulmonary artery pressures (PAP) are normally low and dependent on left atrial pressure (LAP) and cardiac output (CO). Therefore, defining the functi...

journal_title：Progress in cardiovascular diseases

authors： Naeije R,D'Alto M,Forfia PR

更新日期：2015-03-01 00:00:00

abstract：:This study estimates the percentage of health care expenditures in the non-institutionalized United States (U.S.) adult population associated with levels of physical activity inadequate to meet current guidelines. Leisure-time physical activity data from the National Health Interview Survey (2004-2010) were merged wit...

journal_title：Progress in cardiovascular diseases

authors： Carlson SA,Fulton JE,Pratt M,Yang Z,Adams EK

更新日期：2015-01-01 00:00:00

abstract：:Cardiac imaging plays an important role in coronary artery disease (CAD), congestive heart failure (HF) and valvular heart disease (VHD) in the elderly. Imaging defines the structure and function of the cardiac system, refining the understanding of patients' anatomy and physiology and informing a host of clinical care...

journal_title：Progress in cardiovascular diseases

authors： Mehta N,Chokshi NP,Kirkpatrick JN

更新日期：2014-09-01 00:00:00

abstract：:Echocardiography guidance for interventions in the catheterization laboratory allows for reduction in radiation exposure from fluoroscopy as well as superior anatomic definition and visualization. The additional information provided over fluoroscopy has translated into an increasing use during interventional procedure...

journal_title：Progress in cardiovascular diseases

authors： Pislaru SV,Michelena HI,Mankad SV

更新日期：2014-07-01 00:00:00

abstract：:Cardiovascular diseases (CVDs) are the leading cause of death and disability in India. Moreover, mortality following an acute myocardial infarction is high, which may be due to gaps in secondary prevention in general and a lack of cardiac rehabilitation (CR) services in particular. This review discusses the availabili...

journal_title：Progress in cardiovascular diseases

authors： Madan K,Babu AS,Contractor A,Sawhney JP,Prabhakaran D,Gupta R

更新日期：2014-03-01 00:00:00

abstract：:Obesity, particularly severe obesity is capable of producing hemodynamic alterations that predispose to changes in cardiac morphology and ventricular function. These include increased cardiac output, left ventricular hypertrophy and diastolic and systolic dysfunction of both ventricles. Facilitated by co-morbidities s...

journal_title：Progress in cardiovascular diseases

authors： Alpert MA,Omran J,Mehra A,Ardhanari S

更新日期：2014-01-01 00:00:00

abstract：:Telecardiology holds great promise for Africa, from tele-echocardiography and tele-ECG s, to home monitoring and text messaging for medication adherence monitoring. The burden of disease is great and there is an extreme shortage of health professionals. Telemedicine can provide access to scarce specialist care, improv...

journal_title：Progress in cardiovascular diseases

authors： Mars M

更新日期：2013-11-01 00:00:00

abstract：:The epidemiology of cardiovascular diseases in sub-Saharan Africa is unique among world regions, with about half of cardiovascular diseases (CVDs) due to causes other than atherosclerosis. CVD epidemiology data are sparse and of uneven quality in sub-Saharan Africa. Using the available data, the Global Burden of Disea...

journal_title：Progress in cardiovascular diseases

authors： Moran A,Forouzanfar M,Sampson U,Chugh S,Feigin V,Mensah G

更新日期：2013-11-01 00:00:00

abstract：:The QT Variability Index (QTVI) is a non-invasive measure of repolarization lability that has been applied to a wide variety of subjects with cardiovascular disease. It is a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of autonomic nervous system tone. T...

journal_title：Progress in cardiovascular diseases

authors： Dobson CP,Kim A,Haigney M

更新日期：2013-09-01 00:00:00

abstract：:Thoracic aortic aneurysms (TAAs) are a prevalent and deadly disease that, without diagnosis and treatment, eventuates in life-threatening aortic dissection or rupture. While TAAs normally grow in an indolent manner, once a certain size (a "hinge point") is reached, the risk of dissection, rupture, and death increases ...

journal_title：Progress in cardiovascular diseases

authors： Chau KH,Elefteriades JA

更新日期：2013-07-01 00:00:00

abstract：:The revolution in cardiac care over the past two decades, characterized by emergent revascularization, drug eluting stents, anti-platelet medications, and advanced imaging has had little impact on overall ACS recurrence, or ACS prevention. The "Perfect Storm" refers to a confluence of events and processes, including a...

journal_title：Progress in cardiovascular diseases

authors： Burg MM,Edmondson D,Shimbo D,Shaffer J,Kronish IM,Whang W,Alcántara C,Schwartz JE,Muntner P,Davidson KW

更新日期：2013-05-01 00:00:00

abstract：:Left ventricular (LV) dysfunction has been shown to be significantly related to ongoing myocardial ischemia, hibernation, and thus, coronary artery disease. Current treatments for patients with LV dysfunction and concomitant coronary artery disease center around the potential benefit of coronary revascularization, in ...

journal_title：Progress in cardiovascular diseases

authors： Lim MJ,White CJ

更新日期：2013-03-01 00:00:00

abstract：:The first step in the diagnostic evaluation of patients with suspected syncope begins with an "initial evaluation" consisting of careful history taking, physical examination including orthostatic blood pressure measurement and electrocardiogram. However, even in expert centers the diagnostic yield of this "initial eva...

journal_title：Progress in cardiovascular diseases

authors： Blanc JJ

更新日期：2013-01-01 00:00:00

abstract：:The definition of syncope has clinical and pathophysiological parts. The clinical part is that syncope is a form of transient loss of consciousness (TLOC), while the pathophysiological element is that syncope differs from other forms of TLOC by virtue of the basis of true syncope - specifically cerebral hypoperfusion....

journal_title：Progress in cardiovascular diseases

authors： van Dijk JG,Wieling W

更新日期：2013-01-01 00:00:00

abstract：:The success of modern therapies in congenital heart disease has produced a large and growing population of adults with congenital heart disease as a chronic condition. Such success increasingly raises a host of ethical issues, from resource utilization to end of life decision-making. The importance of a multidisciplin...

journal_title：Progress in cardiovascular diseases

authors： Kirkpatrick JN,Kim YY,Kaufman BD

更新日期：2012-11-01 00:00:00

abstract：:Pulmonary artery hypertension is a complex and multi-faceted disease process with numerous etiologies. Chronic thromboembolic pulmonary hypertension (CTEPH) is an underdiagnosed and highly treatable form of pulmonary hypertension. In this disease, certain patients with a history of pulmonary thromboembolic disease go ...

journal_title：Progress in cardiovascular diseases

authors： Haythe J

更新日期：2012-09-01 00:00:00

abstract：:Spurred by large-scale public and private efforts as well as technological developments, the last few years have seen a major leap forward in our understanding of the genetic basis of cardiovascular disease. This revolution is in its infancy and will continue to alter the medical landscape for years to come. There is ...

journal_title：Progress in cardiovascular diseases

authors： Pan S,Knowles JW

更新日期：2012-07-01 00:00:00

abstract：:The recent advent of an entirely subcutaneous implantable defibrillator (ICD) has provided a relevant contribution to the debate concerning the use of ICD therapy in patients at high risk for death. Although conventional transvenous ICDs have proven very effective during the past 23 years, they still appear to be limi...

journal_title：Progress in cardiovascular diseases

authors： Lupo PP,Pelissero G,Ali H,Sanghera R,Cappato R

更新日期：2012-05-01 00:00:00

abstract：:Rigorous training remodels the heart of elite endurance athletes to produce the phenotype of the "athlete's heart." This remodeling, which advantages cardiac performance, creates challenges in the diagnosis of cardiac disorders within this population. This is particularly so for right ventricular pathologies because o...

journal_title：Progress in cardiovascular diseases

authors： Sniderman JD,Sado DM,Sniderman AD,McKenna WJ

更新日期：2012-03-01 00:00:00

abstract：:There is concern in published reports and reviews that patients are being harmed or denied effective treatment by the use of questionable results from secondary analyses of data from clinical trials. A well-reported secondary analysis must make clear to the reader the uncertainty of the result--so clear, in fact, that...

journal_title：Progress in cardiovascular diseases

authors： Marler JR

更新日期：2012-01-01 00:00:00

abstract：:Cardiovascular magnetic resonance (CMR) imaging is a recognized technique for characterization of myocardial tissue in stable ischemic heart disease. In addition, CMR is emerging as a noninvasive imaging tool that can provide supporting information to guide treatment in acute coronary syndromes (ACSs). The advantages ...

journal_title：Progress in cardiovascular diseases

authors： Dall Armellina E,Choudhury RP

更新日期：2011-11-01 00:00:00

abstract：:Over the past decade, emerging clinical trial data supported the usefulness of implanted therapeutic cardiac devices (pacemakers and defibrillators) for the treatment of heart failure (HF). Interest has now developed in evaluating the potential of device diagnostics to identify HF patients at risk for clinical events ...

journal_title：Progress in cardiovascular diseases

authors： Whellan DJ,Adams S,Bowerman L

更新日期：2011-09-01 00:00:00

abstract：:Valvular heart disease (VHD) carries documented risks for active individuals. At the same time, many individuals with intermediate degrees of valve disease can safely exercise and even participate in competitive athletics. Unfortunately for clinicians caring for these patients, data are scarce. Understanding the patho...

journal_title：Progress in cardiovascular diseases

authors： Parker MW,Thompson PD

更新日期：2011-05-01 00:00:00

abstract：:Research to date demonstrates a relationship between exposure to ambient air pollutants and cardiovascular disease (CVD). Many studies have shown associations between short-term exposures to elevated levels of air pollutants and CVD events, and several cohort studies suggest effects of long-term exposure on cardiovasc...

journal_title：Progress in cardiovascular diseases

authors： Gill EA,Curl CL,Adar SD,Allen RW,Auchincloss AH,O'Neill MS,Park SK,Van Hee VC,Diez Roux AV,Kaufman JD

更新日期：2011-03-01 00:00:00

abstract：:Although "congenital heart disease" incorporates a broad and diverse spectrum of inborn cardiac disorders, one shared feature is the propensity for cardiac arrhythmias, albeit to varying degrees. The magnitude of this issue is underscored by its high prevalence, major impact on morbidity and disability, considerable c...

journal_title：Progress in cardiovascular diseases

authors： Abadir S,Khairy P

更新日期：2011-01-01 00:00:00

abstract：:Key questions concerning strategies for diagnosis, prevention, and treatment of heart disease in women remain unanswered. Thrombolytic therapy has been shown to reduce mortality similarly in men and women. In addition, percutaneous coronary intervention for acute coronary syndromes is as effective in women as in men. ...

journal_title：Progress in cardiovascular diseases

authors： Xhyheri B,Bugiardini R

更新日期：2010-11-01 00:00:00

abstract：:Trastuzumab is the standard of care for the treatment of patients with ERB2-positive breast cancer. In a minority of patients, trastuzumab is associated with an increased incidence of cardiac dysfunction that ranges from asymptomatic decreases in left ventricular ejection fraction to symptomatic heart failure. In tria...

journal_title：Progress in cardiovascular diseases

authors： Carver JR

更新日期：2010-09-01 00:00:00

abstract：:The Framingham Heart Study has been a trailblazer in the field of cardiovascular epidemiology. The wealth of novel scientific data that it has generated over 5 decades has made a significant contribution to cardiovascular disease (CVD) prevention in the United States and indirectly influenced global CVD prevention str...

journal_title：Progress in cardiovascular diseases

authors： Mendis S

更新日期：2010-07-01 00:00:00

abstract：:Barometric pressure falls with increasing altitude and consequently there is a reduction in the partial pressure of oxygen resulting in a hypoxic challenge to any individual ascending to altitude. A spectrum of high altitude illnesses can occur when the hypoxic stress outstrips the subject's ability to acclimatize. Ac...

journal_title：Progress in cardiovascular diseases

authors： Imray C,Wright A,Subudhi A,Roach R

更新日期：2010-05-01 00:00:00

abstract：:Massive pulmonary embolism carries a high mortality rate as a result of right ventricular failure. In addition to anticoagulation, systemic thrombolysis is the standard first line of therapy for patients with life-threatening massive pulmonary embolism. Surgical embolectomy is often considered in patients with contrai...

journal_title：Progress in cardiovascular diseases

authors： Todoran TM,Sobieszczyk P

更新日期：2010-03-01 00:00:00

abstract：:A hundred years from its description, Chagas cardiomyopathy remains a challenging disease. Although successful vector-control strategies have decreased the incidence of Chagas disease in several Latin American countries, both migration to urban areas and immigration have spread the disease worldwide; and now, blood tr...

journal_title：Progress in cardiovascular diseases

authors： Biolo A,Ribeiro AL,Clausell N

更新日期：2010-01-01 00:00:00

abstract：:Renal injury distal to an atherosclerotic renovascular obstruction reflects multiple intrinsic factors producing parenchymal tissue injury. Atherosclerotic disease pathways superimposed on renal arterial obstruction may aggravate damage to the kidney and other target organs, and some of the factors activated by renal ...

journal_title：Progress in cardiovascular diseases

authors： Lerman LO,Textor SC,Grande JP

更新日期：2009-11-01 00:00:00

abstract：:Tachycardia is a strong predictor of both hypertension and excessive cardiovascular risk. This association is robust and prevails after multivariate adjustments for other cardiovascular risk factors. Despite the strong evidence, various guidelines do not list tachycardia as a risk factor because of unwarranted assumpt...

journal_title：Progress in cardiovascular diseases

authors： Julius S

更新日期：2009-07-01 00:00:00

abstract：:Infective endocarditis continues to be associated with significant morbidity and mortality despite recent advances in its management and remains a serious and challenging condition requiring a multidisciplinary approach. Surgery is essential in at least 50% of cases. Surgical outcomes have improved with the introducti...

journal_title：Progress in cardiovascular diseases

authors： Zakkar M,Chan KM,Amirak E,Herrey A,Punjabi PP

更新日期：2009-05-01 00:00:00

abstract：:We will review the epidemiology, risk factors, and consequences of obstructive sleep apnea (OSA) and short/long sleep duration. Obstructive sleep apnea is a disease characterized by recurrent upper airway obstruction during sleep. Obstructive sleep apnea is common, with moderate to severe disease present in approximat...

journal_title：Progress in cardiovascular diseases

authors： Al Lawati NM,Patel SR,Ayas NT

更新日期：2009-01-01 00:00:00

abstract：:The changing pattern of disease in the developing world calls for a change in the structure, goals, and personnel of global health assistance. Chronic diseases are now the dominant threat to health and are becoming a challenge to economic advancement in developing economies. Because confronting these diseases, heart d...

journal_title：Progress in cardiovascular diseases

authors： Greenberg H,Raymond SU,Leeder SR

更新日期：2008-07-01 00:00:00